Interview with Professor Garti

Nissim Garti



"Without Nanodroplet Technology,
the effectiveness of natural active ingredients is almost zero!"


- Nissim Garti


As a Professor of Chemistry and Director of the Formulation Department at the Casali Institute of Applied Chemistry in Jerusalem, Professor Nissim Garti specializes in the application of emulsions in medicine, pharmaceuticals and cosmetics. Renowned for his expertise, Professor Garti has been awarded every international prize in chemistry - just short of the Nobel Prize.

Professor Garti holds an impressive number of patents and works as a scientific consultant for world-famous cosmetic brands, yet he chose to work with us at BUTA’I to develop the first natural beauty products based on his proudest discovery: Nanodroplet Technology.

  • Q: Out of all the companies you advise, why did you choose to work with BUTA'I?

    With natural cosmetic products, there is a two-fold problem. First you need a good formulation, which BUTA'I had already achieved. Secondly, you need a good emulsion and, honestly, without Nanodroplet Technology, even the best natural formulation has little chance of success. Individually, both BUTA'I and I were both very strong in our own fields, respectively, but together, we are unbeatable. It was this vital synergy between their research and ours that made me want to work with them.

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  • Q: If the active ingredients were not delivered by Nanodroplet Technology, what would be the result?

    Bioactive ingredients that are insoluble in either water or oil tend to precipitate or separate within the cosmetic formulation even if not seen by the naked eye. Their performance without the Nanodroplet Technology is almost zero.

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  • Q: Why is this technology essential in the context of "all-natural" cosmetics?

    Actually, Nanodroplet Technology it is the only way to insert certain essential natural active ingredients into a cosmetic formula.

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  • Q: In what way are nanodroplets superior to other existing lipid vehicles?

    Nanodroplets are so small (in the nano region) that they enter deeper skin layers in a shorter period of time. They are stable, transparent, able to be fully diluted, monodispersed, soluble, and spontaneously self-assembled. They provide extra performance with regard to all of these points.

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  • Q: What makes your Nanodroplet Technology different?

    Nanodroplet Technology facilitates entrapment of insoluble bioactive ingredients, allowing full dilution, improved bioavailability and transport into dermal layers of the skin.

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  • Q: Has similar research work to yours been conducted anywhere else in the world? What were the results?

    Many labs around the world work on emulsion technologies. The main obstacle they face, and which they have not yet been able to overcome, is related to the physical stability of the molecules developed, and environmental degradation: any degraded byproduct is hazardous to the environment being either volatile (ozone layer) or generating the formation of substances that are not biodegradable and then pollute the Earth.

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  • Q: What led you to work in emulsions?

    I started with the development of a new food additive for the baking industry called SSL, sodium stearoyl lactylate that, at the time, was a new emulsion technology which we held the patent for. Today the product is available, worldwide. Directly from this research I learned to understand the interface between oil and water - the very principle of emulsions.

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